STAT3 Inhibitor Peptide
STAT3 Inhibitor Peptide
from $99.00
| STAT3 Inhibitor Peptide |
| Ac-PpYLKTK-OH |
| A Stat3-SH2 domain binding phosphopeptide that acts as a selective inhibitor of Stat3 (signal transducers and activators of transcription 3) signaling with a DB50 of 235 µM (concentration of peptide at which DNA-binding activity is inhibited by 50%). Significantly lowers the DNA-binding activity of Stat3 by forming an inactive Stat3:peptide complex and reduces the levels of active Stat3:Stat3 dimers that can bind DNA. Displays greater affinity for Stat3, and to a lesser extent Stat1, over Stat5. Supplied as a trifluoroacetate salt. |
| Cat No: | CP794 |
| Peptide Sequence | Ac-Pro-Tyr(PO3H2)-Leu-Lys-Thr-Lys-OH |
| Molecular mass | 870.9 |
| Protect from Light | Yes |
| Hygroscopic | Yes |
| Packaged under inert gas | Yes |
| Purity | ≥95% by HPLC |
| Solubility | H2O |
| Chemical formula | C38H63N8O13P |
| Storage | -20°C |
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