ERK Activation Inhibitor Peptide I, Cell-Permeable
ERK Activation Inhibitor Peptide I, Cell-Permeable
from $100.00
| ERK Activation Inhibitor Peptide I, Cell-Permeable |
| Ste-MEK113, Ste-MPKKKPTPIQLNP-NH2 |
| A cell-permeable stearated 13-amino acid peptide corresponding to the N-terminus of MEK1 (MAPKK) that acts as a specific inhibitor of ERK activation and blocks the transcriptional activity of Elk1. Selectively binds to ERK2 and prevents its interaction with MEK (IC50 = 2.5 µM). Potently blocks ERK activation in PMA-stimulated NIH 3T3 cells and NGF-treated PC12 cells (IC50 = 13 µM). Does not affect the activation of JNKs or p38. |
| Cat No: | CP788 |
| Peptide Sequence | Ste-Met-Pro-Lys-Lys-Lys-Pro-Thr-Pro-Ile-Gln-Leu-Asn-Pro-NH2 |
| Molecular mass | 1757.3 |
| Protect from Light | Yes |
| Hygroscopic | Yes |
| Packaged under inert gas | Yes |
| Purity | ≥95% by HPLC |
| Solubility | DMSO or H2O |
| Chemical formula | C86H153N19O17S |
| Storage | -20°C |
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