DTPA-[Tyr3]-Octreotide
DTPA-[Tyr3]-Octreotide
from $413.00
| DTPA-[Tyr3]-Octreotide, DTPA-TOC |
| DTPA-fCYwKTCT-ol (Disulfide bridge: 2-7) |
| DTPA-Octreotides are a group of compounds comprising DTPA, a metal chelator that carries a radionuclide and octreotide (an octapeptide that is a potent somatostatin (SST)) analog (where DTPA is diethylene triamine pentaacetic acid). Replacement of Phe by Tyr has been shown to increase affinity of DTPA-Octreotide radioconjugates to SST2-positive tumors both in-vitro and in-vivo. This form also has moderately high affinity for SST5 and intermediate affinity for SST3. Studies have shown therapeutic benefits including antimitotic effects and symptomatic cure of malignant insulinomas and gastrinomas. |
| Cat No: | CP4001 |
| Peptide Sequence | DTPA - D - Phe - Cys - Tyr - D - Trp - Lys - Thr - Cys - Thr - ol (Disulfide bridge: 2 - 7) |
| Molecular mass | 1410.6 |
| Protect from Light | Yes |
| Packaged under inert gas | Yes |
| Purity | ≥95% by HPLC |
| Solubility | H2O |
| Storage | -20°C |
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