DTPA-[Tyr3]-Octreotate

DTPA-[Tyr3]-Octreotate

from 413.00
DTPA-[Tyr3]-Octreotate
 
DTPA-fCYwKTCT-OH (Disulfide bridge: 2-7)
 
DTPA-Octreotates are a group of compounds comprising DTPA, a metal chelator that carries a radionuclide and octreotate (an octapeptide that is a potent somatostatin (SST)) analog (where DTPA is diethylene triamine pentaacetic acid). Replacement of Phe by Tyr has been shown to increase affinity of DTPA-Octreotate radioconjugates to SST2-positive tumors both in-vitro and in-vivo. This form also has moderately high affinity for SST5 and intermediate affinity for SST3. Studies have shown therapeutic benefits including antimitotic effects and symptomatic cure of malignant insulinomas and gastrinomas.
Cat No: CP4004
Peptide Sequence DTPA - D - Phe - Cys - Tyr - D - Trp - Lys - Thr - Cys - Thr - OH (Disulfide bridge: 2 - 7)
Molecular mass 1424.6
Protect from Light Yes
Packaged under inert gas Yes
Purity ≥95% by HPLC
Solubility H2O
Storage -20°C
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